Monarch Ortholog Phenotypes
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Mouse (31 sources):
abnormal adipose tissue amount,
abnormal circulating LDL cholesterol level,
abnormal circulating alkaline phosphatase level,
abnormal circulating iron level,
abnormal circulating total protein level,
abnormal lean body mass,
abnormal mean corpuscular hemoglobin,
abnormal nasal bone morphology,
abnormal snout morphology,
abnormal tail morphology,
abnormal zygomatic bone morphology,
asymmetric snout,
decreased Langerhans cell number,
decreased T-helper cell number,
decreased bone mineral content,
decreased effector memory CD8-positive, alpha-beta T cell number,
decreased mature B cell number,
decreased memory-marker CD4-negative NK T cell number,
improved glucose tolerance,
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number,
increased CD4-positive, alpha-beta memory T cell number,
increased CD5-positive gamma-delta T cell number,
increased circulating alkaline phosphatase level,
increased circulating iron level,
increased effector memory CD8-positive, alpha-beta T cell number,
increased lean body mass,
increased mean corpuscular hemoglobin,
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number,
increased red blood cell distribution width,
increased regulatory T cell number,
vertebral transformation
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