serpine2 Phenotypes

Phenotypes

XB-GENEPAGE-947566

Gene Symbol: serpine2 Gene Name: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: serpine2 assayed (11 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (24 sources): abnormal acute phase protein level, abnormal astrocyte morphology, abnormal cerebellar granule layer morphology, abnormal cerebellum external granule cell layer morphology, abnormal copulatory plug formation, abnormal excitatory postsynaptic currents, abnormal excitatory postsynaptic potential, abnormal motor capabilities/coordination/movement, abnormal peripheral nervous system regeneration, abnormal prostate gland physiology, abnormal response to injury, abnormal sciatic nerve morphology, abnormal seminal vesicle epithelium morphology, abnormal seminal vesicle fluid composition, abnormal seminal vesicle morphology, abnormal sensory capabilities/reflexes/nociception, decreased Schwann cell number, dilated seminal vesicles, increased cell proliferation, increased susceptibility to pharmacologically induced seizures, reduced NMDA receptor mediated synaptic activity in barrel cortex, reduced long term potentiation, reduced male fertility, reproductive system phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (24 sources): abnormal acute phase protein level, abnormal astrocyte morphology, abnormal cerebellar granule layer morphology, abnormal cerebellum external granule cell layer morphology, abnormal copulatory plug formation, abnormal excitatory postsynaptic currents, abnormal excitatory postsynaptic potential, abnormal motor capabilities/coordination/movement, abnormal peripheral nervous system regeneration, abnormal prostate gland physiology, [+]