cdh2 Phenotypes

Phenotypes

XB-GENEPAGE-951658

Gene Symbol: cdh2 Gene Name: cadherin 2

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal incomplete closing of the neural tube (1 source), abnormal neural tube closure (1 source), abnormal neural tube morphology (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: cdh2 assayed (1 source)
Computed annotations: cdh2 assayed (7 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + dndvl2 + cdh2 MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (32 sources): abnormal brain development, abnormal cerebral cortex morphology, abnormal cortical ventricular zone morphology, abnormal embryo turning, abnormal heart shape, abnormal heart tube morphology, abnormal impulse conducting system conduction, abnormal intercalated disk morphology, abnormal myocardial fiber morphology, abnormal myocardium layer morphology, abnormal neocortex morphology, abnormal nervous system tract morphology, abnormal radial glial cell morphology, abnormal somite shape, abnormal spinal cord motor column morphology, abnormal visceral yolk sac morphology, abnormal vitelline vasculature morphology, decreased cardiac output, decreased ventricle muscle contractility, dilated heart atrium, dilated heart left ventricle, distended pericardium, ectopic neuron, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, increased neuronal precursor cell number, lethality throughout fetal growth and development, incomplete penetrance, neonatal lethality, complete penetrance, pericardial edema, premature death, prenatal lethality, complete penetrance, wavy neural tube [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (32 sources): abnormal brain development, abnormal cerebral cortex morphology, abnormal cortical ventricular zone morphology, abnormal embryo turning, abnormal heart shape, abnormal heart tube morphology, abnormal impulse conducting system conduction, abnormal intercalated disk morphology, abnormal myocardial fiber morphology, abnormal myocardium layer morphology, [+]