abnormal endocardium morphology, abnormal extraembryonic tissue morphology, abnormal fibroblast migration, abnormal foregut morphology, abnormal hair cycle, abnormal hair follicle orientation, abnormal head fold morphology, abnormal head mesenchyme morphology, abnormal heart development, abnormal innervation, abnormal limb development, abnormal liver development, abnormal lung development, abnormal mesocardium morphology, abnormal mesoderm development, abnormal myocardial fiber morphology, abnormal myocardium layer morphology, abnormal notochord morphology, abnormal placenta vasculature, abnormal rostral-caudal axis patterning, abnormal somite development, abnormal vascular branching morphogenesis, abnormal vascular development, abnormal vascular endothelial cell development, abnormal vascular endothelial cell morphology, abnormal vascular regression, abnormal visceral yolk sac cavity morphology, abnormal vitelline artery morphology, abnormal vitelline vascular remodeling, abnormal vitelline vasculature morphology, absent heartbeat, absent somites, absent vitelline blood vessels, cardiac hypertrophy, cardiac interstitial fibrosis, decreased angiogenesis, decreased body size, decreased embryo size, decreased fibroblast cell migration, decreased fibroblast proliferation, decreased hair follicle number, decreased incidence of tumors by chemical induction, decreased keratinocyte migration, decreased keratinocyte proliferation, decreased sebaceous gland number, decreased survivor rate, decreased tumor growth/size, delayed heart development, delayed hepatic development, dilated heart left ventricle, dilated vasculature, disorganized myocardium, disorganized yolk sac vascular plexus, ectopic Bergmann glia cells, embryonic growth retardation, embryonic lethality between somite formation and embryo turning, complete penetrance, embryonic lethality during organogenesis, complete penetrance, embryonic lethality during organogenesis, incomplete penetrance, enlarged allantois, failure of chorioallantoic fusion, failure of initiation of embryo turning, increased apoptosis, increased keratinocyte apoptosis, increased physiological sensitivity to xenobiotic, increased vascular permeability, lethality throughout fetal growth and development, complete penetrance, lethality throughout fetal growth and development, incomplete penetrance, liver hemorrhage, muscle phenotype, no abnormal phenotype detected, prenatal lethality, complete penetrance, reduced cerebellar foliation, reproductive system phenotype, small amniotic cavity, small visceral yolk sac, thick dermal layer, thick myocardium, thin epidermis, thin placenta labyrinth