pc.1 pyruvate carboxylase, gene 1
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
|Computed annotations: pc.1 assayed (13 sources)|
|Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (17 sources):
Global developmental delay,
Increased serum lactate,
Increased serum pyruvate,
Lactic acidosis, Leukodystrophy, Neuronal loss in the cerebral cortex, Periventricular leukomalacia, Proximal renal tubular acidosis, Psychomotor retardation, Seizure[+]
|Mouse (5 sources): decreased lean body mass, decreased red blood cell distribution width, increased grip strength, increased total body fat amount, preweaning lethality, complete penetrance|
View all ortholog results at Monarch