| Monarch Ortholog Phenotypes
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Human (31 sources):
Abnormal cerebral white matter morphology,
Attention deficit hyperactivity disorder,
Behavioral abnormality,
Blindness,
Bowel incontinence,
Bulbar palsy,
Dementia,
Elevated circulating long chain fatty acid concentration,
Hearing impairment,
Hyperpigmentation of the skin,
Hypogonadism,
Impaired vibration sensation at ankles,
Impotence,
Incoordination,
Limb ataxia,
Loss of speech,
Lower limb muscle weakness,
Mental deterioration,
Neurodegeneration,
Paraparesis,
Polyneuropathy,
Primary adrenal insufficiency,
Psychosis,
Seizure,
Slurred speech,
Spastic paraplegia,
Truncal ataxia,
Urinary bladder sphincter dysfunction,
Urinary incontinence,
Visual loss,
obsolete Hypotrichosis
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Mouse (13 sources):
abnormal Schwann cell morphology,
abnormal adrenal cortex morphology,
abnormal adrenal gland zona fasciculata morphology,
abnormal adrenal gland zona reticularis morphology,
abnormal astrocyte morphology,
abnormal lipid homeostasis,
abnormal locomotor activation,
abnormal microglial cell morphology,
decreased vertical activity,
increased fatty acids level,
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.