bub3 Phenotypes

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Phenotypes

Gene Literature (18)

Nucleotides (407)

Interactants (104)

XB-GENEPAGE-955682

Gene Symbol: bub3 Gene Name: BUB3 mitotic checkpoint protein

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (64 sources): Abnormal aortic morphology, Abnormal cardiovascular system morphology, Abnormal lung lobation, Abnormal skull morphology, Abnormality of immune system physiology, Abnormality of skin pigmentation, Abnormality of the orbital region, Abnormality of the skeletal system, Abnormality of the upper limb, Abnormality of vision, Acute lymphoblastic leukemia, Ambiguous genitalia, Aortic regurgitation, Aplasia/Hypoplasia of the cerebellum, Aplasia/Hypoplasia of the corpus callosum, Apnea, Ascites, Atrial septal defect, Cataract, Cleft palate, Clinodactyly of the 5th finger, Coarctation of aorta, Colon cancer, Corneal opacity, Dandy-Walker malformation, Depressed nasal ridge, Downslanted palpebral fissures, Duodenal atresia, Epicanthus, Frontal bossing, Glaucoma, Global developmental delay, Growth delay, Hearing impairment, High forehead, Holoprosencephaly, Hypothyroidism, Hypotonia, Increased nuchal translucency, Intellectual disability, Intestinal polyposis, Intrauterine growth retardation, Low-set, posteriorly rotated ears, Microcephaly, Micrognathia, Microphthalmia, Multicystic kidney dysplasia, Multiple cafe-au-lait spots, Muscular dystrophy, Myelodysplasia, Neoplasm, Nephroblastoma, Osteolysis, Polyhydramnios, Rhabdomyosarcoma, Seizure, Short stature, Sloping forehead, Stomach cancer, Subvalvular aortic stenosis, Triangular face, Vaginal neoplasm, Ventriculomegaly, Wide nose [+]
Mouse (8 sources): abnormal cell cycle checkpoint function, abnormal cell nucleus morphology, abnormal chromosome morphology, abnormal mitosis, aneuploidy, embryonic lethality between implantation and somite formation, complete penetrance, increased incidence of tumors by chemical induction, inner cell mass degeneration
View all ortholog results at Monarch