gabbr1 Phenotypes

Phenotypes

XB-GENEPAGE-956616

Gene Symbol: gabbr1 Gene Name: gamma-aminobutyric acid (GABA) B receptor, 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: gabbr1 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (40 sources): abnormal CNS synaptic transmission, abnormal action potential, abnormal axon morphology, abnormal conditioned taste aversion behavior, abnormal depression-related behavior, abnormal estrous cycle, abnormal excitatory postsynaptic currents, abnormal habituation to a new environment, abnormal inhibitory postsynaptic currents, abnormal inhibitory postsynaptic potential, abnormal lumbar dorsal root ganglion morphology, abnormal myelin sheath morphology, abnormal neuron physiology, abnormal object recognition memory, abnormal sciatic nerve morphology, abnormal sleep pattern, audiogenic seizures, behavior/neurological phenotype, clonic seizures, decreased locomotor activity, decreased physiological sensitivity to xenobiotic, decreased thermal nociceptive threshold, growth/size/body region phenotype, hyperresponsive to tactile stimuli, hyporesponsive to tactile stimuli, impaired behavioral response to xenobiotic, impaired passive avoidance behavior, increased anxiety-related response, increased circulating prolactin level, increased prepulse inhibition, neonatal lethality, complete penetrance, nervous system phenotype, postnatal lethality, incomplete penetrance, premature death, prolonged estrus, reduced female fertility, reduced long term potentiation, short proestrus, sporadic seizures, weakness [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (40 sources): abnormal CNS synaptic transmission, abnormal action potential, abnormal axon morphology, abnormal conditioned taste aversion behavior, abnormal depression-related behavior, abnormal estrous cycle, abnormal excitatory postsynaptic currents, abnormal habituation to a new environment, abnormal inhibitory postsynaptic currents, abnormal inhibitory postsynaptic potential, [+]