| Monarch Ortholog Phenotypes
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Human (9 sources):
Confusion,
Decreased circulating vitamin B12 concentration,
Dementia,
Malabsorption of Vitamin B12,
Megaloblastic anemia,
Moderate albuminuria,
Paresthesia,
Proteinuria,
Somatic sensory dysfunction
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Mouse (25 sources):
abnormal allantois morphology,
abnormal craniofacial morphology,
abnormal cranium morphology,
abnormal embryo size,
abnormal embryonic tissue morphology,
abnormal endoderm development,
abnormal heart looping,
abnormal pericardium morphology,
abnormal renal reabsorption,
abnormal visceral endoderm morphology,
abnormal vitamin B12 level,
abnormal vitelline vascular remodeling,
abnormal vitelline vasculature morphology,
absent allantois,
absent amnion,
absent chorion,
absent somites,
decreased embryo size,
embryonic lethality during organogenesis, complete penetrance,
failure of initiation of embryo turning,
fused cornea and lens,
iris synechia,
postnatal lethality, incomplete penetrance,
premature death,
preweaning lethality, complete penetrance
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.