| Monarch Ortholog Phenotypes
|
Human (45 sources):
Apraxia,
Astigmatism,
Ataxia,
Broad chin,
Broad nasal tip,
Cerebellar atrophy,
Cryptorchidism,
Decreased fetal movement,
Deep philtrum,
Deeply set eye,
Delayed ability to walk,
Delayed speech and language development,
Downslanted palpebral fissures,
Downturned corners of mouth,
Dysarthria,
Dysmetria,
Dysphagia,
Epicanthus,
Gastroesophageal reflux,
Generalized hypotonia,
Global developmental delay,
High forehead,
Horizontal eyebrow,
Hypertelorism,
Intellectual disability,
Inverted nipples,
Long face,
Low-set ears,
Microcephaly,
Micropenis,
Motor stereotypy,
Myopathic facies,
Oval face,
Overfolded helix,
Poor head control,
Posteriorly rotated ears,
Prominent forehead,
Prominent nasal bridge,
Short chin,
Short stature,
Strabismus,
Synophrys,
Thin upper lip vermilion,
Triangular face,
Vesicoureteral reflux
[+]
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|
Mouse (3 sources):
abnormal sensory neuron innervation pattern,
neonatal lethality, complete penetrance,
small olfactory bulb
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.