| Monarch Ortholog Phenotypes
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Human (44 sources):
Abnormal cardiovascular system morphology,
Abnormal morphology of female internal genitalia,
Abnormality of the voice,
Anosmia,
Anterior hypopituitarism,
Ataxia,
Bimanual synkinesia,
Breast hypoplasia,
Cleft palate,
Color vision defect,
Cryptorchidism,
Decreased fertility,
Decreased testicular size,
Delayed puberty,
Delayed skeletal maturation,
Dysarthria,
Dyspareunia,
Erectile dysfunction,
Gait disturbance,
Gynecomastia,
Hypogonadotropic hypogonadism,
Hypoplasia of penis,
Hyposmia,
Hypothalamic gonadotropin-releasing hormone deficiency,
Hypotonia,
Ichthyosis,
Micropenis,
Muscle weakness,
Nystagmus,
Obesity,
Paraplegia,
Pes cavus,
Pes planus,
Primary amenorrhea,
Ptosis,
Recurrent fractures,
Reduced bone mineral density,
Renal agenesis,
Seizure,
Sensorineural hearing impairment,
Skeletal dysplasia,
Tooth agenesis,
Tremor,
Visual impairment
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Mouse (28 sources):
abnormal axon fasciculation,
abnormal branching involved in ureteric bud morphogenesis,
abnormal cerebral cortex morphology,
abnormal cerebral cortex pyramidal cell morphology,
abnormal dendritic cell physiology,
abnormal dorsal root ganglion morphology,
abnormal neuron differentiation,
abnormal ophthalmic nerve morphology,
abnormal paravertebral ganglion morphology,
abnormal sensory neuron innervation pattern,
abnormal spinal nerve morphology,
abnormal sternum morphology,
abnormal vagus nerve morphology,
asymmetric sternocostal joints,
decreased body size,
decreased brain size,
decreased food intake,
decreased survivor rate,
lethality at weaning, incomplete penetrance,
neonatal lethality, incomplete penetrance,
postnatal lethality, complete penetrance,
postnatal lethality, incomplete penetrance,
premature death,
prenatal lethality, incomplete penetrance,
respiratory system phenotype,
small olfactory bulb,
thin cerebral cortex,
weakness
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.