clpp Phenotypes

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Phenotypes

Gene Literature (0)

Nucleotides (165)

Interactants (106)

XB-GENEPAGE-969407

Gene Symbol: clpp Gene Name: caseinolytic mitochondrial matrix peptidase proteolytic subunit

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: clpp assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (8 sources): Congenital sensorineural hearing impairment, Hypergonadotropic hypogonadism, Hypoplasia of the uterus, Microcephaly, Primary amenorrhea, Seizure, Sensorineural hearing impairment, Short stature
Mouse (54 sources): abnormal T cell activation, abnormal adipose tissue amount, abnormal body length, abnormal bone mineralization, abnormal cellular respiration, abnormal circulating bilirubin level, abnormal circulating cholesterol level, abnormal circulating fructosamine level, abnormal granulosa cell morphology, abnormal hemoglobin content, abnormal lean body mass, abnormal mean corpuscular hemoglobin, abnormal oogenesis, abnormal red blood cell distribution width, abnormal seminiferous tubule epithelium morphology, arrest of spermatogenesis, decreased CD4-positive NK T cell number, decreased NK T cell number, decreased body length, decreased bone mineral content, decreased circulating fructosamine level, decreased circulating glucose level, decreased corpora lutea number, decreased effector memory CD8-positive, alpha-beta T cell number, decreased fibroblast proliferation, decreased gamma-delta T cell number, decreased lean body mass, decreased locomotor activity, decreased memory-marker CD4-negative NK T cell number, decreased memory-marker CD4-positive NK T cell number, decreased red blood cell distribution width, decreased startle reflex, decreased susceptibility to weight gain, decreased vertical activity, dermatitis, disorganized mitochondrial cristae, early cellular replicative senescence, increased KLRG1-positive NK cell number, increased Ly6C high monocyte number, increased Ly6C low monocyte number, increased bone mineral content, increased circulating alkaline phosphatase level, increased circulating iron level, increased embryonic tissue cell apoptosis, increased granulosa cell apoptosis, increased lean body mass, increased mature B cell number, increased mean corpuscular hemoglobin, increased mitochondrial DNA content, increased mitochondrial size, increased total body fat amount, premature death, preweaning lethality, incomplete penetrance, small ovary [+]
View all ortholog results at Monarch