| Monarch Ortholog Phenotypes
|
|
Human (14 sources):
Abnormal peristalsis,
Chronic diarrhea,
Cognitive impairment,
Congenital shortened small intestine,
Decreased intestinal transit time,
Displacement of the urethral meatus,
Failure to thrive,
Intestinal hypoplasia,
Intestinal malrotation,
Lipoatrophy,
[+]
|
Mouse (21 sources):
abnormal blood homeostasis,
abnormal cecum position,
abnormal digestive system morphology,
abnormal duodenum topology,
abnormal gastrointestinal motility,
abnormal intestinal peristalsis,
abnormal intestinal smooth muscle morphology,
abnormal intestine physiology,
abnormal intestine placement,
abnormal renal tubule morphology,
abnormal ureter physiology,
abnormal ureter smooth muscle morphology,
decreased body size,
decreased survivor rate,
distended cecum,
impaired ureteric peristalsis,
increased intestine length,
increased systemic arterial systolic blood pressure,
postnatal lethality, incomplete penetrance,
preweaning lethality, incomplete penetrance,
slow postnatal weight gain
[+]
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.