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Summary Expression Phenotypes Gene Literature (12) GO Terms (4) Nucleotides (112) Proteins (46) Interactants (102) Wiki

hira     histone cell cycle regulator

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
decreased length of anterior-posterior axis (3 sources), decreased size of the head (3 sources), decreased size of the tail (3 sources), abnormal gastrulation (2 sources), abnormally delayed closure of blastopore (2 sources), abnormal anterior-posterior axis, curved dorsal (1 source), abnormal anterior-posterior axis, curved lateral (1 source), increased apoptosis in embryo (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: hira manipulated (1 source)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + hira MO (4 sources), Xla Wt + hira MO (1 source), Xla Wt + hira MO (1 source), Xla Wt + hira MO (1 source), Xla Wt + hira MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (1 source): Cognitive impairment
Mouse (39 sources): abnormal allantois morphology, abnormal axial mesoderm morphology, abnormal brain development, abnormal developmental patterning, abnormal embryo development, abnormal embryo turning, abnormal embryonic neuroepithelium morphology, abnormal embryonic tissue morphology, abnormal head mesenchyme morphology, abnormal heart development, [+]

View all ortholog results at Monarch