rbfox3 Phenotypes

Phenotypes

XB-GENEPAGE-976380

Gene Symbol: rbfox3 Gene Name: RNA binding fox-1 homolog 3

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: rbfox3 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (30 sources): abnormal CNS synaptic transmission, abnormal brain white matter morphology, abnormal dendritic spine morphology, abnormal dentate gyrus neuron dendrite morphology, abnormal excitatory postsynaptic potential, abnormal excitatory synapse morphology, abnormal hippocampus granule cell morphology, abnormal hippocampus neuron morphology, abnormal hippocampus physiology, abnormal miniature excitatory postsynaptic currents, abnormal miniature inhibitory postsynaptic currents, abnormal neuron differentiation, abnormal object recognition memory, abnormal thermal nociception, behavior/neurological phenotype, decreased anxiety-related response, decreased brain weight, decreased circulating alkaline phosphatase level, decreased grip strength, decreased neuronal precursor cell number, decreased neuronal precursor proliferation, decreased paired-pulse facilitation, impaired spatial learning, impaired synaptic plasticity, increased neurotransmitter release, increased sensitivity to xenobiotic induced morbidity/mortality, increased startle reflex, increased susceptibility to pharmacologically induced seizures, nervous system phenotype, reduced long term depression [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (30 sources): abnormal CNS synaptic transmission, abnormal brain white matter morphology, abnormal dendritic spine morphology, abnormal dentate gyrus neuron dendrite morphology, abnormal excitatory postsynaptic potential, abnormal excitatory synapse morphology, abnormal hippocampus granule cell morphology, abnormal hippocampus neuron morphology, abnormal hippocampus physiology, abnormal miniature excitatory postsynaptic currents, [+]