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Summary Expression Phenotypes Gene Literature (22) GO Terms (2) Nucleotides (95) Proteins (34) Interactants (63) Wiki

scn1a     sodium channel, voltage gated, type I alpha subunit

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: scn1a assayed (4 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (87 sources): Abnormal brainstem morphology, Abnormal periventricular white matter morphology, Abnormality of movement, Abnormality of retinal pigmentation, Abnormality of the dentition, Aggressive behavior, Anxiety, Ataxia, Atonic seizure, Atypical absence seizure, [+]
Mouse (53 sources): abnormal GABA-mediated receptor currents, abnormal RR interval, abnormal action potential, abnormal brain wave pattern, abnormal cerebellar molecular layer, abnormal dendrite morphology, abnormal dendritic spine morphology, abnormal excitatory postsynaptic currents, abnormal habituation to a novel odor, abnormal hippocampus granule cell morphology, [+]

View all ortholog results at Monarch