pofut1 Phenotypes

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Phenotypes

Gene Literature (2)

Nucleotides (164)

Interactants (202)

XB-GENEPAGE-979242

Gene Symbol: pofut1 Gene Name: protein O-fucosyltransferase 1

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal head morphology (2 sources), abnormal trunk region (2 sources), decreased size of the main body axis (2 sources)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: pofut1 manipulated (1 source)
Computed annotations: pofut1 assayed (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + nodal1 + pofut1 MO (1 source), Xla Wt + pofut1 (1 source), Xla Wt + pofut1 MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (4 sources): Follicular hyperkeratosis, Hyperkeratotic papule, Hypomelanotic macule, Reticular hyperpigmentation
Mouse (38 sources): abnormal atrioventricular cushion morphology, abnormal bronchiole epithelium morphology, abnormal cardiac epithelial to mesenchymal transition, abnormal dorsal-ventral polarity of the somites, abnormal heart development, abnormal mammary gland growth during pregnancy, abnormal somite development, abnormal somite shape, abnormal somite size, abnormal vasculogenesis, abnormal vertebral column morphology, abnormal vitelline vasculature morphology, absent club cells, absent intersomitic vessels, absent vertebral spinous process, absent vitelline blood vessels, decreased birth body size, decreased body length, decreased body size, decreased embryo size, distended pericardium, embryonic growth retardation, embryonic lethality during organogenesis, embryonic lethality during organogenesis, complete penetrance, embryo phenotype, epidermal cyst, failure of heart looping, fused somites, increased solitary pulmonary neuroendocrine cell number, kinked neural tube, kinked tail, myocardial trabeculae hypoplasia, postnatal lethality, incomplete penetrance, premature death, prenatal lethality, reproductive system phenotype, respiratory system phenotype, short tail [+]
View all ortholog results at Monarch