daam1 Phenotypes

Phenotypes

XB-GENEPAGE-983771

Gene Symbol: daam1 Gene Name: dishevelled associated activator of morphogenesis 1

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal anterior-posterior axis morphology (2 sources), abnormal cilium assembly (2 sources), abnormally decreased number of ciliated cell (2 sources), abnormally delayed closure of blastopore (1 source), absent blastopore (1 source), absent upper blastopore lip (1 source), obsolete decreased cilium motility in ciliated epidermal cell (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: daam1 manipulated (2 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + daam1 MO (4 sources), Xla Wt + dnHsa.daam1 (2 sources), Xla Wt + daam1 MO (1 source), Xla Wt + daam1 MO (1 source), Xla Wt + daam1 MO + mtss1.2 MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (19 sources): abnormal blood urea nitrogen level, abnormal cell adhesion, abnormal diastolic filling velocity, abnormal fetal cardiomyocyte morphology, abnormal fibroblast physiology, abnormal pulmonary pressure, abnormal sarcomere morphology, cardiovascular system phenotype, decreased body size, decreased embryo size, decreased fetal size, decreased right ventricle systolic pressure, decreased survivor rate, impaired wound healing, increased fasting circulating glucose level, lethality throughout fetal growth and development, incomplete penetrance, neonatal lethality, incomplete penetrance, preweaning lethality, complete penetrance, thin ventricle myocardium compact layer [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (19 sources): abnormal blood urea nitrogen level, abnormal cell adhesion, abnormal diastolic filling velocity, abnormal fetal cardiomyocyte morphology, abnormal fibroblast physiology, abnormal pulmonary pressure, abnormal sarcomere morphology, cardiovascular system phenotype, decreased body size, decreased embryo size, [+]