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Summary Expression Phenotypes Gene Literature (5) GO Terms (7) Nucleotides (86) Proteins (37) Interactants (209) Wiki

irf8     interferon regulatory factor 8

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: irf8 assayed (8 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (11 sources): Abnormality of immune system physiology, Bronchiectasis, Fever, Immunodeficiency, Lymphadenopathy, Oral ulcer, Pneumonia, Recurrent infections, Recurrent respiratory infections, Sinusitis, [+]
Mouse (36 sources): abnormal cytotoxic T cell physiology, abnormal definitive hematopoiesis, abnormal erythropoiesis, abnormal humoral immune response, abnormal megakaryocyte morphology, abnormal myelopoiesis, abnormal plasma cell number, abnormal sleep behavior, abnormal spleen marginal zone morphology, decreased bone mineral content, [+]

View all ortholog results at Monarch