Capillary leak, Decreased fertility, Decreased serum estradiol, Delayed puberty, Delayed skeletal maturation, Enlarged polycystic ovaries, Generalized edema, Gonadal dysgenesis, Hearing impairment, Hemorrhagic ovarian cyst, Hirsutism, Hypovolemia, Increased circulating gonadotropin level, Increased serum testosterone level, Microcephaly, Nausea, Nausea and vomiting, Osteopenia, Osteoporosis, Osteoporosis of vertebrae, Ovarian cyst, Peripheral edema, Pleural effusion, Premature ovarian insufficiency, Primary amenorrhea, Pulmonary edema, Pulmonary fibrosis, Reduced bone mineral density, Secondary amenorrhea, Short stature, Sparse pubic hair, Streak ovary

abnormal female germ cell morphology, abnormal fertility/fecundity, abnormal granulosa cell morphology, abnormal grip strength, abnormal lean body mass, abnormal mammary gland morphology, abnormal ovarian follicle number, abnormal ovarian folliculogenesis, abnormal ovarian secretion, abnormal ovulation, abnormal proestrus, abnormal seminiferous tubule epithelium morphology, abnormal seminiferous tubule morphology, abnormal sperm axoneme morphology, abnormal sperm flagellum morphology, abnormal sperm head morphology, abnormal sperm nucleus morphology, abnormal sperm physiology, abnormal spermatid morphology, abnormal spermatogonia morphology, abnormal spermatogonia proliferation, abnormal spermiogenesis, abnormal startle reflex, abnormal testes secretion, abnormal testis development, abnormal thoracic vertebrae morphology, abnormal thrombosis, abnormal uterine environment, abnormal uterus morphology, abnormal vagina epithelium morphology, abnormal vagina orifice morphology, absent corpus luteum, absent estrous cycle, absent estrus, absent mature ovarian follicles, absent oocytes, absent ovarian follicles, adenohypophysis hyperplasia, anovulation, asthenozoospermia, decreased Sertoli cell number, decreased bone mineral content, decreased circulating estradiol level, decreased circulating progesterone level, decreased epididymis weight, decreased femur weight, decreased grip strength, decreased lean body mass, decreased litter size, decreased luteinizing hormone level, decreased ovary weight, decreased primary ovarian follicle number, decreased seminal vesicle weight, decreased testis weight, decreased uterus weight, decreased vagina weight, delayed female fertility, delayed male fertility, detached acrosome, early reproductive senescence, early vaginal opening, enlarged endometrial glands, enlarged sperm head, hippocampal neuron degeneration, hunched posture, impaired ovarian folliculogenesis, increased anxiety-related response, increased apoptosis, increased cell proliferation, increased circulating estradiol level, increased circulating prolactin level, increased follicle recruitment, increased follicle stimulating hormone level, increased gonadotroph cell number, increased litter size, increased luteinizing hormone level, increased ovarian carcinoma incidence, increased pituitary gland weight, increased pre-B cell number, increased prolactinoma incidence, increased thigmotaxis, increased thyrotroph cell number, increased total fat pad weight, increased uterus weight, kinked sperm flagellum, long gestation period, myometrium hypoplasia, neonatal lethality, complete penetrance, oocyte degeneration, ovary atrophy, ovary hemorrhage, pituitary gland hyperplasia, polyovular ovarian follicle, postnatal lethality, incomplete penetrance, premature aging, prolonged diestrus, prolonged estrous cycle, reduced female fertility, reduced male fertility, small caput epididymis, small epididymis, small ovary, small seminal vesicle, small seminiferous tubules, small uterus, thin uterus, uterine hemorrhage, uterus adenomyosis, uterus atrophy, uterus cyst, vagina atrophy