ssbp2 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-987285

Gene Symbol: ssbp2 Gene Name: single-stranded DNA binding protein 2

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal pronephric tubule morphology (5 sources), decreased size of the pronephric tubule (3 sources), abnormally decreased number of proximal tubule (2 sources), abnormal development of pronephric duct (1 source), abnormal development of pronephric kidney (1 source), abnormal distal tubule morphology (1 source), abnormal glomus morphology (1 source), abnormal pronephric duct morphology (1 source), decreased size of the distal tubule (1 source), decreased size of the eye (1 source), decreased size of the glomus (1 source), decreased size of the head (1 source), decreased size of the proximal tubule (1 source), edematous embryo (1 source), increased pigmentation in the head (1 source)

Anatomical Phenotypes

Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.

abnormal pronephric tubule morphology (5 sources), decreased size of the pronephric tubule (3 sources), abnormally decreased number of proximal tubule (2 sources), abnormal development of pronephric duct (1 source), abnormal development of pronephric kidney (1 source), abnormal distal tubule morphology (1 source), abnormal glomus morphology (1 source), abnormal pronephric duct morphology (1 source), decreased size of the distal tubule (1 source), decreased size of the eye (1 source), decreased size of the glomus (1 source), decreased size of the head (1 source), decreased size of the proximal tubule (1 source), edematous embryo (1 source), increased pigmentation in the head (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: ssbp2 manipulated (4 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla WT + ssbp2 MO (9 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (24 sources): abnormal adipose tissue amount, abnormal body length, abnormal bone mineralization, abnormal epididymis morphology, abnormal grip strength, abnormal kidney morphology, abnormal lean body mass, decreased body length, decreased bone mineral content, decreased brain weight, decreased grip strength, enlarged epididymis, increased B cell derived lymphoma incidence, increased adenoma incidence, increased jejunum adenocarcinoma incidence, increased lean body mass, increased lung adenoma incidence, increased lymphoma incidence, increased malignant tumor incidence, increased pre-B cell number, increased startle reflex, perinatal lethality, incomplete penetrance, premature death, small heart [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (24 sources): abnormal adipose tissue amount, abnormal body length, abnormal bone mineralization, abnormal epididymis morphology, abnormal grip strength, abnormal kidney morphology, abnormal lean body mass, decreased body length, decreased bone mineral content, decreased brain weight, [+]