cyp1a1 Phenotypes

Phenotypes

XB-GENEPAGE-990172

Gene Symbol: cyp1a1 Gene Name: cytochrome P450 family 1 subfamily A member 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: cyp1a1 assayed (1 source)
Computed annotations: cyp1a1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (17 sources): abnormal hemoglobin content, abnormal xenobiotic pharmacokinetics, decreased hematocrit, decreased physiological sensitivity to xenobiotic, decreased sensitivity to xenobiotic induced morbidity/mortality, decreased spleen weight, decreased thymus weight, homeostasis/metabolism phenotype, increased circulating alanine transaminase level, increased circulating aspartate transaminase level, increased liver weight, increased neutrophil cell number, increased physiological sensitivity to xenobiotic, increased susceptibility to weight loss, no abnormal phenotype detected, small spleen, small thymus [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (17 sources): abnormal hemoglobin content, abnormal xenobiotic pharmacokinetics, decreased hematocrit, decreased physiological sensitivity to xenobiotic, decreased sensitivity to xenobiotic induced morbidity/mortality, decreased spleen weight, decreased thymus weight, homeostasis/metabolism phenotype, increased circulating alanine transaminase level, increased circulating aspartate transaminase level, [+]