| Monarch Ortholog Phenotypes
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Human (24 sources):
Abnormality of eye movement,
Ankle clonus,
Ataxia,
Babinski sign,
Difficulty walking,
Distal sensory impairment,
Dysarthria,
Dysmetria,
Functional abnormality of the bladder,
Gait ataxia,
Hyperreflexia in upper limbs,
Limb ataxia,
Lower limb hyperreflexia,
Lower limb muscle weakness,
Lower limb spasticity,
Nystagmus,
Peripheral neuropathy,
Pes cavus,
Pes valgus,
Scoliosis,
Sensory axonal neuropathy,
Skeletal muscle atrophy,
Spastic paraplegia,
Urinary incontinence
[+]
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|
Mouse (8 sources):
abnormal blood coagulation,
abnormal leukocyte adhesion,
abnormal platelet dense granule physiology,
decreased physiological sensitivity to xenobiotic,
decreased ventricle muscle contractility,
hematopoietic system phenotype,
increased heart weight,
premature death
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.