pdpk1 Phenotypes

Summary

Expression

Phenotypes

Gene Literature (0)

XB-GENEPAGE-991548

Gene Symbol: pdpk1 Gene Name: 3-phosphoinositide dependent protein kinase 1

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (80 sources): abnormal CD8-positive, alpha beta T cell morphology, abnormal NK T cell morphology, abnormal T cell differentiation, abnormal Z line morphology, abnormal adrenal gland zona fasciculata morphology, abnormal allantois morphology, abnormal brain development, abnormal cephalic neural fold morphology, abnormal craniofacial morphology, abnormal developmental patterning, abnormal embryo development, abnormal embryonic tissue morphology, abnormal endoderm development, abnormal extraembryonic tissue morphology, abnormal eye pigmentation, abnormal first pharyngeal arch morphology, abnormal forelimb morphology, abnormal head development, abnormal kidney size, abnormal melanotroph morphology, abnormal myocardial fiber morphology, abnormal neural crest cell physiology, abnormal neuron physiology, abnormal pancreatic beta cell morphology, abnormal pituitary intermediate lobe morphology, abnormal placenta development, abnormal presomitic mesoderm morphology, abnormal rostral-caudal body axis extension, abnormal vasculogenesis, absent NK T cells, absent dorsal root ganglion, absent forebrain, absent heart, absent heart tube, absent pharyngeal arches, absent somites, cardiovascular system phenotype, decreased NK T cell number, decreased T cell proliferation, decreased birth body size, decreased body size, decreased brain size, decreased cardiac muscle contractility, decreased circulating glucose level, decreased corticotroph cell number, decreased embryo size, decreased forebrain size, decreased gonadal fat pad weight, decreased insulin secretion, embryo phenotype, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, enlarged heart atrium, immune system phenotype, improved glucose tolerance, incomplete embryo turning, increased circulating glucose level, increased corticotroph apoptosis, increased food intake, increased insulin sensitivity, increased melanotroph apoptosis, increased pituitary gland apoptosis, increased total body fat amount, maternal effect, myocardium hypoplasia, nervous system phenotype, no abnormal phenotype detected, pancreatic islet hyperplasia, pancreatic islet hypoplasia, perinatal lethality, complete penetrance, premature death, prenatal lethality, complete penetrance, prenatal lethality, incomplete penetrance, short mandible, small allantois, small heart, small pancreas, small pancreatic islets, small spleen, thin ventricular wall [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (80 sources): abnormal CD8-positive, alpha beta T cell morphology, abnormal NK T cell morphology, abnormal T cell differentiation, abnormal Z line morphology, abnormal adrenal gland zona fasciculata morphology, abnormal allantois morphology, abnormal brain development, abnormal cephalic neural fold morphology, abnormal craniofacial morphology, abnormal developmental patterning, [+]