dcx Phenotypes

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Phenotypes

Gene Literature (12)

Nucleotides (76)

Interactants (136)

XB-GENEPAGE-992091

Gene Symbol: dcx Gene Name: doublecortin

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: dcx assayed (2 sources)
Computed annotations: dcx assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (18 sources): Agenesis of corpus callosum, Agyria, Ataxia, Axial hypotonia, Dysarthria, Failure to thrive, Feeding difficulties, Gray matter heterotopia, Hypotonia, Intellectual disability, Intellectual disability, severe, Lissencephaly, Micropenis, Motor delay, Nystagmus, Pachygyria, Seizure, Spasticity [+]
Mouse (14 sources): abnormal avoidance learning behavior, abnormal brain interneuron morphology, abnormal hippocampal mossy fiber morphology, abnormal hippocampus CA3 region morphology, abnormal hippocampus pyramidal cell layer, abnormal inhibitory postsynaptic currents, abnormal rostral migratory stream morphology, abnormal spatial learning, decreased body size, decreased grip strength, loss of hippocampal neurons, postnatal lethality, incomplete penetrance, premature death, reduced male fertility [+]
View all ortholog results at Monarch