tnfrsf1a Phenotypes

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Phenotypes

Gene Literature (4)

Nucleotides (105)

Interactants (159)

XB-GENEPAGE-996079

Gene Symbol: tnfrsf1a Gene Name: TNF receptor superfamily member 1A

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: tnfrsf1a assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (45 sources): Abdominal pain, Abnormal myocardium morphology, Abnormal sacroiliac joint morphology, Amyloidosis, Arthralgia, Arthritis, Behavioral abnormality, Bruising susceptibility, Cellulitis, Chest pain, Conjunctival hyperemia, Conjunctivitis, Constipation, Cranial nerve paralysis, Diarrhea, Edema, Elevated circulating C-reactive protein concentration, Elevated erythrocyte sedimentation rate, Erysipelas, Erythema, Fasciitis, Hepatic amyloidosis, Hypermelanotic macule, Intestinal obstruction, Leukocytosis, Lymphadenopathy, Macule, Migraine, Muscle stiffness, Myalgia, Myositis, Orchitis, Paresthesia, Pericarditis, Periorbital edema, Peritonitis, Pleuritis, Recurrent fever, Recurrent pharyngitis, Skin rash, Splenomegaly, Uveitis, Vasculitis, Vertigo, Vomiting [+]
Mouse (57 sources): abnormal Peyer's patch follicle morphology, abnormal Peyer's patch morphology, abnormal airway responsiveness, abnormal circulating total protein level, abnormal follicular dendritic cell morphology, abnormal glutamate-mediated receptor currents, abnormal intestine physiology, abnormal large unstained cell number, abnormal lymph node B cell domain morphology, abnormal macrophage physiology, abnormal neuron proliferation, abnormal oval cell physiology, abnormal red blood cell distribution width, abnormal respiratory mechanics, abnormal response/metabolism to endogenous compounds, abnormal sleep pattern, abnormal spleen germinal center morphology, abnormal spleen weight, absent follicular dendritic cells, decreased IgG1 level, decreased Peyer's patch number, decreased circulating alanine transaminase level, decreased circulating interleukin-1 beta level, decreased circulating interleukin-6 level, decreased interleukin-6 secretion, decreased microglial cell number, decreased physiological sensitivity to xenobiotic, decreased red blood cell distribution width, decreased sensitivity to induced morbidity/mortality, decreased sensitivity to xenobiotic induced morbidity/mortality, decreased spleen weight, decreased susceptibility to autoimmune diabetes, decreased susceptibility to bacterial infection, decreased susceptibility to dopaminergic neuron neurotoxicity, decreased susceptibility to endotoxin shock, decreased susceptibility to experimental autoimmune encephalomyelitis, decreased tumor incidence, granulomatous inflammation, immune system phenotype, impaired adaptive thermogenesis, impaired central nervous system regeneration, impaired humoral immune response, impaired skin barrier function, increased circulating alanine transaminase level, increased circulating tumor necrosis factor level, increased interleukin-6 secretion, increased large unstained cell number, increased neutrophil cell number, increased sensitivity to induced cell death, increased sensitivity to induced morbidity/mortality, increased skin papilloma incidence, increased susceptibility to bacterial infection induced morbidity/mortality, increased susceptibility to endotoxin shock, increased susceptibility to experimental autoimmune encephalomyelitis, increased susceptibility to parasitic infection, increased susceptibility to type I hypersensitivity reaction, tumor regression [+]
View all ortholog results at Monarch