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Summary Expression Phenotypes Gene Literature (93) GO Terms (23) Nucleotides (150) Proteins (32) Interactants (204) Wiki
XB-GENEPAGE-5994597
???displayGene.symbol???:
 chrna4

???displayGene.name???: 
cholinergic receptor, nicotinic alpha 4

???displayGene.synonyms???
bfnc , ebn , ebn1 , nachr , nAChR , nachra4 [+] ( Nomenclature history )

???displayGene.geneFunction???
Ultrahigh sulfur keratin-associated protein

Protein Function :
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.


InterPro :
Neurotransmitter ion chnl CS, Neur chan lig-bd sf, Neur chan lig-bd, Neuro-gated channel TM sf, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
autosomal dominant nocturnal frontal lobe epilepsy [+]

MIM:
TOBACCO ADDICTION, SUSCEPTIBILITY TO [+]

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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