The adra1a gene encodes an alpha-1 adrenergic receptor, a G-protein coupled receptor localized to the plasma membrane which binds catecholamines and mediates their effects through intracellular signali...[+]

The adra1a gene encodes an alpha-1 adrenergic receptor, a G-protein coupled receptor localized to the plasma membrane which binds catecholamines and mediates their effects through intracellular signaling pathways involving phosphatidylinositol-calcium second messengers; it is expressed in the brain, including the telencephalon and diencephalon, spinal cord, cranial ganglia, and pronephros. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD