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Summary Expression Phenotypes Gene Literature (240) GO Terms (245) Nucleotides (370) Proteins (50) Interactants (1603) Wiki
XB-GENEPAGE-484285
???displayGene.symbol???:
 tp53

???displayGene.name???: 
tumor protein p53

???displayGene.synonyms???
p53 , Trp248 , tumor suppressor p53 , Xp53 , Xrel3 [-] ( Nomenclature history )

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transcription factor regulating cell cycle, apoptosis and TGF-beta signaling

Protein Function :
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator tha...[+]


InterPro :
p53 DNA-bd, p53/RUNT-type TF DNA-bd sf, p53 tetramer sf, p53 tetrameristn, [+]

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Diseases: 


Disease Ontology:
chronic lymphocytic leukemia [+]

MIM:
HEPATOCELLULAR CARCINOMA [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
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???displayGene.mosmith??? tneu034a23      


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