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Summary Expression Phenotypes Gene Literature (7) GO Terms (50) Nucleotides (152) Proteins (48) Interactants (168) Wiki
XB-GENEPAGE-855790
???displayGene.symbol???:
 appl1

???displayGene.name???: 
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

???displayGene.synonyms???
appl , dip13alpha ( Nomenclature history )

???displayGene.geneFunction???
signal transduction

AI Protein Function :
The appl1 gene encodes an adaptor protein which binds to the small GTPase Rab5 and is associated with membranes during early development, including in the neural plate. It plays a role in eye developme...[+]


InterPro :
AH/BAR dom sf, BAR dom, DP13A/B, DP13A BAR, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
maturity-onset diabetes of the young

MIM:
MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 14; MODY14

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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