The gene strc encodes a stereocilin protein localized to stereocilia of hair cells in the inner ear and lateral line system. It functions as an extracellular matrix protein important for the structural...[+]

The gene strc encodes a stereocilin protein localized to stereocilia of hair cells in the inner ear and lateral line system. It functions as an extracellular matrix protein important for the structural organization and cohesion of the stereociliary bundle. [-]

             autosomal recessive nonsyndromic deafness 16
             azoospermia
             spermatogenic failure 7

          DEAFNESS, AUTOSOMAL RECESSIVE 16; DFNB16
          DEAFNESS-INFERTILITY SYNDROME; DIS

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD