The gene tpst2 encodes a tyrosylprotein sulfotransferase enzyme that catalyzes the sulfation of tyrosine residues in secreted proteins and proteoglycans. In Xenopus laevis and Xenopus tropicalis, the t...[+]

The gene tpst2 encodes a tyrosylprotein sulfotransferase enzyme that catalyzes the sulfation of tyrosine residues in secreted proteins and proteoglycans. In Xenopus laevis and Xenopus tropicalis, the tpst2 protein functions in protein tyrosine O-linked sulfation, which is critical for protein-protein interactions and signaling pathways. This enzyme is localized to the Golgi apparatus and is involved in post-translational modifications that affect protein function and stability. The tpst2 protein is expressed in various tissues, including the developing nervous system, where it influences cell signaling and morphogenesis. Its activity is essential for proper embryonic development and tissue patterning. [-]

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