The htr2c gene encodes a G-protein coupled receptor that binds serotonin, localizing to the plasma membrane and intracellular vesicles. In neurons, it is involved in signaling pathways. This receptor m...[+]

The htr2c gene encodes a G-protein coupled receptor that binds serotonin, localizing to the plasma membrane and intracellular vesicles. In neurons, it is involved in signaling pathways. This receptor mediates melanosome dispersion within dermal melanophores of the skin. Expression is observed in specific brain regions including the telencephalon, diencephalon, mesencephalon, and rhombencephalon, as well as the spinal cord and retina. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD