Eukaryotic translation initiation factor 3 subunit i (eif3i) is a cytoplasmic protein component of the eIF3 complex that binds RNA and facilitates ribosome assembly for cap-dependent translation initia...[+]

Eukaryotic translation initiation factor 3 subunit i (eif3i) is a cytoplasmic protein component of the eIF3 complex that binds RNA and facilitates ribosome assembly for cap-dependent translation initiation. It is expressed in the oocyte and throughout early embryonic development, with maternal mRNA contributing to initial stages. The protein localizes to the cytoplasm where it functions as part of the multi-subunit eIF3 complex involved in the recruitment of the 43S pre-initiation complex to mRNA. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD