Gene Symbol:  wdr45b Gene Name:  WD repeat domain 45B Synonyms: ( Nomenclature history ) Gene Function: Uncharacterized conserved protein, contains WD40 repeats Protein Function : Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation...[+] Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. In the cellular response to starvation, may also function in the inhibition of the mTORC1 signaling pathway. [-] InterPro : WD40 repeat dom sf , WD40 repeat , WD40/YVTN repeat-like dom sf Interactants: Loading ... Diseases:  OMIM: NEURODEVELOPMENTAL DISORDER WITH SPASTIC QUADRIPLEGIA AND BRAIN ABNORMALITIES WI External Links: ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD

Expression	Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information	Xenbase Expression Details In situ images Single cell data at SPRING

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