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Summary Expression Phenotypes Gene Literature (7) GO Terms (12) Nucleotides (205) Proteins (46) Interactants (118) Wiki
XB-GENEPAGE-481915
Gene Symbol:
 psen1

Gene Name: 
presenilin 1

Synonyms:
X-PS-alpha , X-PS-beta ( Nomenclature history )

Gene Function:
intracellular signaling

Protein Function :
Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.


InterPro :
Preselin/SPP , Presenilin C , Peptidase A22A , Znf-3CxxC [+]

Interactants:
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Diseases: 


Disease Ontology:
Alzheimer's disease 3 [+]

OMIM:
ALZHEIMER DISEASE 3; AD3 [+]

External Links:
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info