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Summary Expression Phenotypes Gene Literature (40) GO Terms (26) Nucleotides (258) Proteins (39) Interactants (427) Wiki
XB-GENEPAGE-489916
Gene Symbol:
 cxcr4

Gene Name: 
C-X-C motif chemokine receptor 4

Synonyms:
xcxcr4 , fb22 , hm89 , lap3 , lcr1 , npyr [+] ( Nomenclature history )

Gene Function:
G protein-coupled receptor

Protein Function :
Receptor for the C-X-C chemokine cxcl12/sdf-1. Transduces a signal by increasing the intracellular level of calcium ions. Signaling with cxcl12/sdf-1 mediates the directional movement of mesodermal cel...[+]


InterPro :
GPCR Rhodpsn 7TM , CXCR4/ACKR2 , Chemokine rcpt , GPCR Rhodpsn [+]

Interactants:
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Diseases: 


Disease Ontology:
WHIM syndrome

OMIM:
WHIM SYNDROME 1; WHIMS1

External Links:
1/2
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info