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Summary Expression Phenotypes Gene Literature (76) GO Terms (6) Nucleotides (231) Proteins (58) Interactants (743) Wiki
XB-GENEPAGE-493519
Gene Symbol:
 axin2

Gene Name: 
axin 2 (conductin, axil)

Synonyms:
axil , xarp , conductin ( Nomenclature history )

Gene Function:
G protein signaling regulator

Protein Function :
Regulates the wnt signaling pathway by interacting with dvl2/dsh, which displaces gsk3b from the axnr-gsk3b complex and thus prevents degradation of ctnnb1/beta-catenin.


InterPro :
HERPUD1/2 , Ubiquitin-like domsf , Ubiquitin-like dom , EF-hand-dom pair [+]

Interactants:
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Diseases: 


Disease Ontology:
tooth agenesis [+]

OMIM:
COLORECTAL CANCER; CRC [+]

External Links:
1/2
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info