Gene Symbol:  tbc1d23 Gene Name:  TBC1 domain family member 23 Synonyms: ( Nomenclature history ) Gene Function: Uncharacterized conserved protein, contains TBC and Rhodanese domains Protein Function : Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, located a...[+] Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Plays a role in brain development. May act as a general inhibitor of innate immunity signaling. [-] InterPro : Ser/Thr kinase AS , Kinase-like dom sf , Prot kinase dom , Ferritin-like diiron [+] , Ferritin CS , Ferritin DPS dom , Ferritin-like , Ferritin , Ferritin-like SF [-] Interactants: Loading ... Diseases:  Disease Ontology: pontocerebellar hypoplasia type 11 OMIM: PONTOCEREBELLAR HYPOPLASIA, TYPE 11; PCH11 External Links: ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD

Expression	Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information	Xenbase Expression Details In situ images Single cell data at SPRING

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