Gene Symbol:  ubr1 Gene Name:  ubiquitin protein ligase E3 component n-recognin 1 Synonyms: ( Nomenclature history ) Gene Function: N-end rule pathway, recognition component UBR1 Protein Function : Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leadin...[+] Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. [-] InterPro : UBR1-like , WH DNA-bd sf , Ribosomal L7/12 C/ClpS-like , Znf UBR [+] , ClpS core [-] Interactants: Loading ... Diseases:  Disease Ontology: Johanson-Blizzard syndrome OMIM: JOHANSON-BLIZZARD SYNDROME; JBS External Links: ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD

Expression	Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information	Xenbase Expression Details In situ images Single cell data at SPRING

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