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Summary Expression Phenotypes Gene Literature (231) GO Terms (11) Nucleotides (362) Proteins (44) Interactants (1588) Wiki
XB-GENEPAGE-484285
Gene Symbol :
tp53
Symbol Status : Curated


Gene Name :
tumor protein p53
Name Status : Curated


Synonyms:
p53 , Xp53 , Trp248 , Xrel3 , tumor suppressor p53 [-] ( Add synonyms , Nomenclature history )

Gene Function:
transcription factor regulating cell cycle, apoptosis and TGF-beta signaling

Protein Function :
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator tha...[+]


InterPro :
RecA ATP-bd , DNA repair Rad51/TF NusA a-hlx , DNA recomb/repair Rad51 C , RecA monomer-monomer interface [+]

Interactants:
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Diseases: 


Disease Ontology:
chronic lymphocytic leukemia [+]

OMIM:
HEPATOCELLULAR CARCINOMA [+]

External Links:
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Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
Phenotype
Smith Morpholino Screen tneu034a23      

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info