Gene Symbol:  cep63 Gene Name:  centrosomal protein 63kDa Synonyms: xcep63 ( Nomenclature history ) Gene Function: Dystonin, GAS (Growth-arrest-specific protein), and related proteins Protein Function : Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication. Plays a role in DNA damage response: following DNA double strand breaks (DSBs), it is delocal...[+] Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication. Plays a role in DNA damage response: following DNA double strand breaks (DSBs), it is delocalized from centrosomes due to phosphorylation by atm and atr, leading to inactivate spindle assembly and delay mitotic progression. [-] InterPro : Cep63 , Cep63/Deup1 N Interactants: Loading ... Diseases:  Disease Ontology: Seckel syndrome 6 OMIM: SECKEL SYNDROME 6; SCKL6 External Links: ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD

Expression	Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information	Xenbase Expression Details In situ images Single cell data at SPRING

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