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Summary Expression Phenotypes Gene Literature (174) GO Terms (16) Nucleotides (91) Proteins (49) Interactants (556) Wiki
XB-GENEPAGE- 487473

Show:     All X. tropicalis X. laevis

Protein sequences for nodal2 - All


Models (34)

Source Version Model Species
NCBI 10.1 XBmRNA26234 X. laevis.L
NCBI 10.1 XBmRNA28549 X. laevis.S
NCBI 10.0 mRNA019755 X. tropicalis
ENSEMBL 10.0 ENSXETP00000098022 X. tropicalis
Xenbase 9.2 rna52998 X. laevis.L
JGI 9.1 Xelaev18020132m X. laevis.S
Xenbase 9.1 rna26902 X. tropicalis
JGI 9.1 Xelaev18018870m X. laevis.L
ENSEMBL 9.1 ENSXETP00000098022 X. tropicalis
JGI 8.0 Xetrov14012271m X. tropicalis
JGI 7.2 Xelaev16020574m X. laevis.L
JGI 7.1 Xetro.C00175.1 X. tropicalis
JGI 6.0 XeXenL6RMv10013039m X. laevis.L
JGI 6.0 XeXenL6RMv10023903m X. laevis.L
JGI 4.1 fgenesh1_pg.C_scaffold_34000162 X. tropicalis
JGI 4.1 e_gw1.34.449.1 X. tropicalis
JGI 4.1 fgenesh1_pm.C_scaffold_34000066 X. tropicalis
JGI 4.1 gw1.34.449.1 X. tropicalis
JGI 4.1 gw1.34.450.1 X. tropicalis
JGI 4.1 gw1.34.451.1 X. tropicalis
JGI 4.1 fgenesh1_pg.C_scaffold_34000163 X. tropicalis
JGI 4.1 e_gw1.34.450.1 X. tropicalis
JGI 4.1 e_gw1.34.451.1 X. tropicalis
ENSEMBL 4.1 ENSXETP00000019728 X. tropicalis
ENSEMBL 4.1 ENSXETP00000019729 X. tropicalis
JGI 4.1 estExt_fgenesh1_kg.C_340039 X. tropicalis
JGI 4.1 estExt_fgenesh1_pg.C_340160 X. tropicalis
JGI 4.1 estExt_fgenesh1_pg.C_340161 X. tropicalis
JGI 4.1 estExt_fgenesh1_pm.C_340065 X. tropicalis
JGI 4.1 estExt_FilteredModels1.C_340134 X. tropicalis
JGI 4.1 estExt_Genewise1.C_340449 X. tropicalis
JGI 4.1 estExt_Genewise1.C_340450 X. tropicalis
JGI 4.1 estExt_Genewise1.C_340451 X. tropicalis
JGI 4.1 fgenesh1_kg.C_scaffold_34000040 X. tropicalis

UniProtKB Protein Function: Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos. Essential for mesoderm formation and axial patterning during embryonic development. Activates the activin-like signaling pathway to induce dorsal and ventral mesoderm in animal cap ectoderm. In addition, also dorsalizes ventral marginal zone (VMZ) tissues during gastrulation. Induces muscle actin. Appears to act as both a short-range and long-range morphogen. The unprocessed protein inhibits bmp- and wnt-signaling.

AI Protein Function : Nodal2 is a secreted signaling molecule of the tgf-beta superfamily. It is involved in mesendoderm induction, left-right asymmetry patterning, and axial mesoderm development. The protein functions in the left-right organizer, dorsal blastopore lip, and gastrocoel roof plate. Its activity is implicated in the formation of the notochord.

NCBI Proteins (15)

Accession Species Source
KAE8619493 X. tropicalis RefSeq
KAE8619494 X. tropicalis RefSeq
XP_002932767 X. tropicalis NCBI Protein
AAA97393 X. laevis.L NCBI Protein
AAI69388 X. laevis.L NCBI Protein
AAI69392 X. laevis.L NCBI Protein
NP_001081436 X. laevis.L RefSeq
OCT90258 X. laevis.L NCBI Protein
AAL02115 X. laevis.S NCBI Protein
OCT86449 X. laevis.S RefSeq
XP_018110489 X. laevis.S RefSeq

UniProt Proteins (4)

Accession Species Source
A0A6I8SKM0 (InterPro) X. tropicalis TrEMBL
A0A974HU65 (InterPro) X. laevis.L TrEMBL
B7ZPA9 (InterPro) X. laevis.L TrEMBL
Q91620 (InterPro) X. laevis.L Swiss-Prot