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XB-GENEPAGE-
5868905
Protein sequences for mt-co1 - All
Models (0)
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UniProtKB Protein Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
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AI Protein Function  :
The mt-co1 protein is a cytochrome c oxidase subunit and functions as part of mitochondrial complex iv in the electron transport chain, facilitating the transfer of electrons to molecular oxygen for atp production. Its subcellular localization is within the mitochondrion, specifically embedded in the inner mitochondrial membrane.
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NCBI Proteins (5)
| Accession | Species | Source |
AAV49100
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X. tropicalis | NCBI Protein |
| YP_203372
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X. tropicalis | NCBI Protein |
| AAA66460
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Generic inactive organism | NCBI Protein |
| NP_008136
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Generic inactive organism | RefSeq |
UniProt Proteins (1)
| Accession | Species | Source |
| Q5G7I8
(InterPro)
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X. tropicalis | Swiss-Prot |