Gene Expression Search Experiment

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Gene/Clone	Species	Stage	Anatomy Item	Experimenter
acvr2a	xenopus		intersomitic region

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Experiment details for acvr2a

Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage.

Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage.

Gene	Clone	Species	Stages	Anatomy
acvr2a.L		laevis	NF stage 33 and 34 to NF stage 35 and 36	intersomitic region

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Fig. S1. BMP type II receptors. Type II receptors complement type I receptors and can potentially interact with any type I receptor with ligands being the determinant of the nature of heterocomplexes. Bmpr2 is not expressed at gastrulation, but its expression is activated in the ventral mesoderm from stage 16, later extending to almost all tissues. At stages 34–39, Bmpr2 is also expressed in the DA. Acvr2a is expressed ubiquitously at all stages analyzed. Acvr2b is expressed ubiquitously at gastrulation but later display a restricted expression pattern, being expressed predominantly in neurons. Acvr2b is localized to DA at stage 39. Embryos at stages 10.5 and 34–39 are cleared to enable visualization of the staining in deeper tissues. For stage 10.5 embryos, D indicates dorsal and V indicates the ventral side. For stages 16–20, embryos are visualized from dorsal (D) and ventral (V) angles, with anterior (A) at the top, except stage 16 bmp4 staining, which is documented from an anterior–posterior (A-P) lateral view. From stage 21 onward, the pictures of embryos are taken from a lateral view, with anterior-posterior labeled where it is relevant, on the figure.