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Experiment details for cacna1d



Cloning and characterization of voltage-gated calcium channel alpha1 subunits in Xenopus laevis during development.

Gene Clone Species Stages Anatomy
cacna1d.L laevis NF stage 24 to NF stage 26 forebrain , midbrain , hindbrain , spinal cord , pineal gland , [+]
cacna1d.L laevis NF stage 29 and 30 to NF stage 31 otic vesicle , forebrain , midbrain , hindbrain , spinal cord , [+]
cacna1d.L laevis NF stage 33 and 34 to NF stage 35 and 36 otic vesicle , forebrain , midbrain , hindbrain , spinal cord , [+]

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  Figure 2. Spatial and temporal expression patterns of VGCC alpha 1 subunits in developing X. laevis embryos using whole-mount in situ hybridization. Embryos were viewed laterally, with anterior to the left and dorsal to the top. A,D,G,J,M,P,S,V,Y: Stages 24-26 (early tail bud). B,E,H,K,N,Q,T,W,Z: Stages 29-31 (late tail bud). C,F,I,L,O,R,U,X,AA: Stages 34-36 (swimming tadpole). A-C: CaV1.1 expression. D-F: CaV1.2 expression. G-I: CaV1.3 expression. J-L: CaV1.4 expression. M-O: CaV2.1 expression. P-R: CaV2.2 expression. S-U: CaV2.3 expression. V-X: CaV3.1 expression. Y-AA: CaV3.2 expression. D prime ,F prime ,S prime ,T prime ,W prime ,Y prime : Magnified images of portions of the embryos indicated by the hollow boxes. AA prime : Magnified image of the tail of an embryo at swimming tadpole stage showing CaV3.2 expression. Arrowheads indicate regions of expression. fb, forebrain; e, eye; hb, hindbrain; ht, heart; mb, midbrain; oe, olfactory epithelium; ot, otic vesicle; pa, pharyngeal arches; pg, pineal gland; sc, spinal cord; so, somite; t, tail bud; V, cranial ganglion V, trigeminal ganglion; VII, cranial ganglion VII, geniculate (facialis) ganglion; IX, cranial ganglion IX, glossopharyngeal ganglion; X, cranial ganglion X, vagal ganglion. Scale bars = 1.0 mm in A-AA, 0.4 mm in AA prime ; 0.2 mm in D prime ,F prime ,S prime ,T prime ,W prime ,Y prime .