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eedxenopus   

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Experiment details for eed

Snail2/Slug cooperates with Polycomb repressive complex 2 (PRC2) to regulate neural crest development.

Snail2/Slug cooperates with Polycomb repressive complex 2 (PRC2) to regulate neural crest development.

Gene Clone Species Stages Anatomy
eed.L laevis NF stage 10 involuted dorsal mesoderm
eed.L laevis NF stage 11 mesoderm , involuted dorsal mesoderm
eed.L laevis NF stage 18 neural crest , optic vesicle , cranial neural crest
eed.L laevis NF stage 27 olfactory placode , otic vesicle , mandibular crest , hyoid crest , neural crest , [+]
eed.L laevis NF stage 35 and 36 otic vesicle , midbrain-hindbrain boundary , neural crest , mandibular arch , hyoid arch , [+]

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  Fig. 1. Expression of the PRC2 core components during early Xenopus development. Eed, Ezh2 and Suz12 are expressed similarly in early Xenopus embryos. Their transcripts are detected in the pan-mesoderm in late blastulae and early gastrulae embryos, but are shifted to dorsal mesodermal and dorsal ectodermal cells at late gastrula stages. During neurulation, their RNAs are located in neural and neural crest cells. At tailbud and tadpole stages, these genes are expressed in neural, sensory organs and migrating neural crest cells.