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Experiment details for fst

Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity.

Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity.

Gene Clone Species Stages Anatomy
fst.L laevis NF stage 14 to NF stage 35 and 36 ventricular zone , notochord , hypochord , dorsal , neural tube

  Figure 4. Transverse Sections of Embryos Stained by Whole-Mount In Situ Hybridization for XFS-319 RNA Distribution (A) Transverse section of a late gastrula (stage 11.5). Animal pole is at the top, dorsal to the left, and ventral to the right. XFS-319 RNA is exclusively localized to the dorsal side of the embryo. RNA staining is perinuclear and restricted to cells in the deep layer, prechordal mesoderm, and anterior chordal mesoderm. The arrow marks the yolk plug. (B) Transverse section of an early neurula (stage 14) embryo showing the localization of XFS RNA in the notochord, just underneath the open neural plate, and the cells of the hypochord. (C) Transverse section through the forebrain of a swimming tadpole, showing that XFS RNA is localized as three dorsoventral stripes in the cells of the ventricular zone (arrows). Staining is absent from the floor plate and roof plate. For both (B) and (C), dorsal side is at the top.