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Gene/Clone	Species	Stage	Anatomy Item	Experimenter
gipc2	xenopus		chordal neural plate [+] Mauthner cell,astrocyte,astrocyte end-foot,central canal,cerebellum,dorsal column nucleus,dorsal funiculus,floor plate,fourth ventricle,granule cell,granule cell layer of the cerebellum,lateral funiculus,locus coeruleus,medulla oblongata,nucleus of the solitary tract,nucleus reticularis inferior,nucleus reticularis medialis,nucleus reticularis superior,oligodendrocyte,raphe nucleus,rhombic lip,rhombomere,roof plate,solitary tract,spinal neuron,ventral funiculus,hindbrain,posterior neural tube,spinal cord

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Experiment details for gipc2

Eukaryotic initiation factor eIF6 modulates the expression of Kermit 2/XGIPC in IGF- regulated eye development.

Eukaryotic initiation factor eIF6 modulates the expression of Kermit 2/XGIPC in IGF- regulated eye development.

Gene	Clone	Species	Stages	Anatomy
gipc2.L		laevis	NF stage 14 to NF stage 16	chordal neural plate

Fig. 3. Relationship between eif6 and gipc2 expression. a. In situ hybridization performed using gipc2 anti-sense RNA on neurula injected at the 2 cell stage in one blastomere with either GFP (1 and 4), eif6 (2 and 5) or S235A (3 and 6). In GFP injected embryos (1 and 4), the hybridization intensity and pattern is identical in the embryo dorsal portion (1) and in the eye field territory (4, arrows) of both sides. In both eif6 (2 and 5) and S235A (3−6) injected samples, gipc2 is expressed at a lower level in the injected side than in the un-injected side, in particular in the eye field territory (arrows). βgal mRNA was visualized with Red-Gal. b. Real-time PCR using embryos injected with increasing concentration of eif6 (100, 200 and 400 pg) shows a highly significant (P<0.001) dose-dependent decrease of gipc2 mRNA. c. Real-time PCR in eif6 morphants showing a highly significant increase of gipc2 mRNA (P<0001) in contrast to the control mis-paired morpholino.