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Figure 7. Mel1a melatonin receptor-immunoreactive processes in the outer plexiform layer (OPL) contact cone photoreceptor terminals. A: Branches of Mel1a-immunoreactive processes (green; arrows) ascend through the OPL to contact the terminals of calbindin-immunoreactive cone photoreceptors (red; arrowheads) terminals. Confocal image stack comprised of 11 optical slices of ≈400 nm each. B: Mel1a melatonin receptor-immunoreactive processes (green; arrowheads) in the OPL contact XAP-1-immunoreactive cone photoreceptor terminals (red). The extracellular matrix surrounding the inner and outer segments of the photoreceptors is also XAP-1-immunoreactive. Confocal image stack comprised of 10 optical slices of ≈400 nm each. Nuclei are counterstained with DAPI (blue) in both panels. PH, photoreceptor inner segments; ONL, outer nuclear layer; INL, inner nuclear layer. Scale bars = 10 μm in both panels. |
